DNA_sequencer.md

(Yellow‑zone draft)

DNA Sequencer#

DNA sequencers infer nucleotide order through chemical, optical, or electronic signals. Their operation is powerful but relies on multi‑step inference and substrate‑sensitive chemistry.

Dimensional Core (SET)#

• Spin: not relevant
• Elec: detector readout
• Temp: critical for reaction stability

Why Yellow‑Zone#

Sequencers work well but depend on complex biochemical regimes with many hidden assumptions. Calibration masks drift, and environmental conditions strongly influence results.

Regime Notes#

• pos‑regime: stable chemistry, controlled temperature
• Q‑regime: reagent variability, partial reactions
• neg‑regime: contamination, thermal instability

Alignment Notes#

Needs explicit regime boundaries and clarity around inference layers.